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Buy Zinacef, Ceftin (Cefuroxime) No RX 125/250/500mg

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Zinacef (Cefuroxime) 750mg and 250mg Tablets

Read all of this leaflet carefully before you start taking this medicine.

  • Keep this leaflet. You may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

What Zinacef is and what it is used for

Read indications for use if you want to order Cefuroxime online

What Zinacef is

Zinacef 1.5 g, 750 mg or 250 mg (called ‘Zinacef in this leaflet) is a cephalosporin antibiotic for intravenous (IV) injection or infusion or intramuscular (IM) infusion. The intravenous injection or infusion is made into a vein and intramuscular infusion is made into a muscle. Zinacef contains a medicine called cefuroxime (present as cefuroxime sodium).

What Zinacef is used for

Zinacef is used to treat infections in different parts of the body caused by bacteria.

Before you take Zinacef

Before buy Cefuroxime online, read information about the drug

Do not take Zinacef if you:

  • are allergic (hypersensitive) to cefuroxime, cefuroxime sodium or cephalosporin antibiotics
  • have ever had an allergic (hypersensitive) reaction to any antibiotic. This can include a skin rash or swelling of the face or neck
  • have kidney problems

Do not take Zinacef if any of the above apply. If you are not sure, talk to your doctor, pharmacist or nurse before having Zinacef.

Meningitis

Please note that like other medicines used to treat meningitis, Zinacef may take a while to clear the body of all the meningitis infection. Because of this, hearing loss caused by meningitis has occurred in a few patients after using Zinacef to treat the disease.

Blood tests

If you are having any blood tests, let the doctor or nurse know that you are on Zinacef. This is because Zinacef can affect the results of these tests.

Taking other medicines

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes medicines that can be bought without a prescription and herbal medicines. This is because Zinacef can affect the way some other medicines work. Also some other medicines can affect the way Zinacef works.

Zinacef should not be taken without first discussing this with your doctor if you are also taking:

  • water tablets (diuretics) such as furosemide

If you still need to have Zinacef, you will have regular tests to check your kidneys.

  • aminoglycoside-type antibiotics such as neomycin or gentamycin

Zinacef may stop the contraceptive pill working. You will need to use extra contraceptive precautions, such as using a condom. If you need any advice, talk to your doctor or pharmacist.

Pregnancy and breast-feeding

Ask your doctor or pharmacist for advice before taking any medicine if you think you might be or if you are pregnant or if you are breast-feeding.

Important information about one of the ingredients of Zinacef

Zinacef 1.5 g contains 81.29 mg of sodium. Zinacef 750 mg contains 40.65 mg of sodium. Zinacef 250 mg contains 13.55 mg of sodium. This should be considered if you are on a controlled sodium diet.

How Zinacef is given

When you buy cheap Cefuroxime you must know how to use it

You will never give yourself this medicine. A qualified person, like a doctor or a nurse, will give you this medicine.

  • The correct dose of Zinacef will be decided by your doctor and depends on the type of infection, whether you are on any other antibiotics and your weight and age.
  • If your condition has not improved within 72 hours of receiving treatment, the doctor will review your treatment.
  • Zinacef will usually be given by a doctor or nurse either directly into a vein (IV) or into a muscle (IM). In some cases, it may be added to a “drip” or intravenous infusion. Zinacef is made up by adding the following amount of Water for Injections or other recommended diluting solution.
Vial size Intramuscularinjection (suspension) Intravenous injection (solution) Intravenous infusion (solution)
250 mg 1 ml at least 2 ml
750 mg 3 ml at least 6 ml
1.5g 15 ml
short1.5ginfusion(up to 30minutes) 50 ml

The usual doses are given below.

Adults

  • Most infections: 750 mg three times a day by IM or IV
  • More severe infections: 1.5 g three times a day IV

The frequency of the IM or IV injection can be increased to 6 hourly if necessary, giving total doses of between 3 g and 6 g per day.

Pneumonia

1.5 g twice a day IV or IM for 48 to 72 hours followed by treatment with another medicine, Zinnat® Tablets (500 mg twice a day for 7 days).

The duration of treatment with Zinacef or Zinnat will depend on how severe your infection is and how well you are responding to the treatment.

  • Chronic bronchitis: 750 mg twice a day IV or IM for 48 to 72 hours followed by treatment with another medicine, Zinnat Tablets (500 mg twice a day for 5 to 7 days).

The duration of treatment with Zinacef or Zinnat will depend on how severe your infection is and how well you are responding to the treatment.

  • Gonorrhoea (a sexually transmitted disease): a single 1.5 g dose. This may be given as 2 x 750 mg injections.
  • Meningitis: 3 g by IV every 8 hours.
  • To stop infections during and after abdominal, pelvic or orthopaedic surgery: 1.5 g by IV when you have your anaesthetic.

It may be supplemented with 2 x 750 mg IM doses 8 and 16 hours later.

  • To stop infections during and after total joint replacement surgery: 1.5 g of unmade up powder may be mixed with the material used to make the joint.
  • To stop infections during and after cardiac, pulmonary, oesophageal and vascular surgery: 1.5 g by IV when you have your anaesthetic. It may be supplemented with 750 mg IM three times a day for a further 24 to 48 hours.

Babies over one month and Children

  • Most infections: 60 mg per kilogram of the child’s body weight per day. Doses will be given in 3 to 4 divided doses. Doses of 30 mg to 100 mg per kilogram of the child’s body weight per day may be given.
  • Meningitis: 200 mg to 240 mg by IV per kilogram per day in 3 or 4 divided doses. This may be reduced to 100 mg per kilogram per day IV after 3 days or when the baby or child starts to get better.

Newborn babies up to one month

  • Most infections: 30 mg to 100 mg per kilogram of the child’s body weight per day may be given in 2 to 3 divided doses.
  • Meningitis: The initial dose will be 100 mg by IV per kilogram of the child’s body weight per day. However, the doctor may prescribe 50 mg by IV per kilogram per day.

Elderly patients and patients with kidney problems

If you are elderly or have kidney problems:

  • you may be given a different dose to the usual dose. The doctor or nurse will advise how much Zinacef you will need, depending on the severity of any kidney disease
  • your doctor will keep a close check on you and you may have more regular kidney function tests.

If you have too much Zinacef

It is unlikely you will be given too much, but if you think you have been given too much Zinacef, tell your doctor, pharmacist or nurse immediately. Signs might include fits (convulsions).

If you have any further questions on the use of this product, ask your doctor or pharmacist.

Possible side effects

Read side effects if you want cheap Cefuroxime no prescription

Like all medicines, Zinacef can cause side effects, although not everybody gets them. Very rarely, a sudden and severe allergic reaction to Zinacef can occur. If you get any of the following symptoms tell your doctor, pharmacist or nurse immediately:

  • Swelling of the face, lips, tongue or other parts of the body.
  • Breathing difficulties.

Other side effects include:

The following is uncommon (affects less than 1 in 100 people)

  • high temperature (fever), chills, a sore throat or other signs of an infection or if they bruise more easily. These may be signs of a problem with your blood cells.

The following are very rare (affects less than 1 in 10,000 people)

  • inflammation of the large bowel (colon) with diarrhoea sometimes containing blood, pain and fever
  • a skin reaction known as ‘erythema multiforme’ where you may develop: itchy reddish-purple patches on the skin especially on the palms of the hands or the soles of the feet, ‘hive-like’ raised swollen areas on the skin, tender areas of the surfaces of the mouth, eyes and private parts. You may have a fever and be very tired
  • other severe skin reactions can include: changes in skin colour, bumps under the skin, blistering, pustules, peeling, redness, pain, itch, scaling.These may be associated with fever, headaches and body aches
  • rash or pinpoint flat red round spots under the skin surface or bruising of the skin. This is due to inflammation of blood vessel walls due to an allergic reaction. It can be associated with joint pain (arthritis) and kidney problems

If any of the above happen to you speak to your doctor or nurse straight away as your medicine should be stopped.

Sometimes you may get less severe skin reactions such as:

  • A mildly itchy rash (round, pink-red patches), ‘hive-like’ swollen areas on forearms, legs, palms, hands, or feet.This is uncommon (affects less than 1 in 100 people).

If you have this talk to your doctor or nurse as Zinacef will need to be stopped.

The other possible side effects are:

Common (affects less than 1 in 10 people)

  • changes to your white blood cells which might make you more susceptible to infections
  • a brief rise in the amount of liver enzymes in your body which might show up if you have a blood test
  • pain or inflammation at the site of the injection.

Uncommon (affects less than 1 in 100 people)

  • skin rashes
  • itching
  • false positive red blood cell status tests (Coombs or rhesus test)
  • a decrease in the number of red blood cells in your blood, a symptom may be tiredness
  • feeling sick (nausea)
  • diarrhoea
  • stomach pain

Rare (affects less than 1 in 1,000 people)

  • thrush (a yeast infection of the vagina, mouth or skin folds), you can get treatment for thrush from your doctor or pharmacist
  • the blood may take longer to clot than it normally would. You may notice this if you have a nosebleed or cut yourself
  • a fever associated with an allergic reaction which disappears on discontinuation

Very rare (affects less than 1 in 10,000 people)

  • an excessive breakdown of red blood cells causing a form of anaemia. Signs include: tiredness, headaches, shortness of breath, dizziness, looking pale and yellowing of the skin and the whites of the eyes
  • inflammation of blood vessels in the skin
  • kidney problems.

If any of the side effects get serious, or if you have any side effects not listed in this leaflet, please tell your doctor or pharmacist.

How to store Zinacef

Before purchase Cefuroxime, you must read how to store

Zinacef is for use in hospital only and the expiry date and storage instructions stated on the vial label and carton are for the doctor, nurse or pharmacist’s information. The doctor, pharmacist or nurse will make up your medicine.

Further information

What Zinacef contains

  • The active substance is 1.5 g, 750 mg or 250 mg of cefuroxime (present as cefuroxime sodium).
  • There are no other ingredients. However, see section 2 for further important information about one of the ingredients of Zinacef, sodium.

What Zinacef looks like and contents of the pack

Zinacef 1.5 g, 750 mg or 250 mg is supplied as white to cream powder in moulded glass vials with a rubber bung and flip-off cap. Each individual vial is packed in a carton.These are supplied to the hospital in packs of 1 (1.5 g), 5 (250 mg and 750 mg) or 100 (750 mg). Your doctor, pharmacist or nurse will make the injection up with Water for Injections for your muscle or vein injection. When made up for injection into a muscle, it becomes off-white and opaque. When made up for injection into a vein, it is yellowish.

Marketing Authorisation Holder and Manufacturer

Marketing Authorisation Holder: GlaxoSmithKline UK, Stockley Park West, Uxbridge, Middlesex. UB11 1BT

Manufacturer: GlaxoSmithKline Manufacturing S.p.A., Verona, Italy

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Zinacef-water 1.5 gm/50 ml      

Synonyms of Cefuroxime:

Cefuroxim, Cefuroxime [USAN:BAN:INN], Cefuroximo [INN-Spanish], Cefuroximum [INN-Latin]

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Therapeutic classes of Cefuroxime:

Anti-Bacterial Agents, Cephalosporins

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