Endocarditis is an inflammation of the endocardium, the membrane lining the chambers of the heart and covering the cusps of the heart valves. Infective endocarditis refers to infection of the heart valves by microorganisms. Endocarditis is often referred to as either acute or subacute depending on the clinical presentation. Acute bacterial endocarditis is a fulminating infection associated with high fevers, systemic toxicity, and death within a few days to weeks if untreated.

Treatment of Endocarditis

The most important approach to treatment of Infective endocarditis includes isolation of the infecting pathogen and determination of antimicrobial susceptibilities, followed by high-dose, bactericidal antibiotics for an extended period.

Evaluation of therapeutic outcomes

Treatment of Staphylococcal Endocarditis in the Presence of a Prosthetic Valve or Other Prosthetic Material.