Sepsis and Septic Shock

Lipid A is a part of the endotoxin molecule that is highly immunoreactive and is responsible for most of the toxic effects. Endotoxin first associates with a protein called lipopolysaccharide-binding protein in plasma.

Management of Sepsis

Sepsis, sepsis syndrome, septic shock, and multiorgan dysfunction are all part of a continuum of infection-related systemic illness. Table Definitions for Sepsis, Sepsis Syndrome, Septic Shock and Multiorgan Dysfunction Syndrome gives definitions for each of these entities. The pathogenesis of sepsis is very complex, involving a large number of mediators.


Sepsis. Description of Medical Condition. Medical Symptoms and Signs of Disease. What Causes Disease?