Antifungal drugs

Lomexin a Potent Antifungal

Lomexin is a drug applied in gynecological and dermatological praxis to treat a wide spectrum of fungal infections both intravaginal and those affecting external genitals. The medication can also be applied to other infected areas of the skin. It contains Fenticonazole nitrate as an active component.

Kill Fungal Infection with Lotrisone

Containing two active ingredients, Lotrisone can effectively deal with inflammatory fungal infections of the skin. Clotrimazole helps to take control of the fungus growth, whereas Betamethasone (which is a corticosteroid) reduces redness, itching, and inflammation of the infected area of the skin.

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A white or almost white, hygroscopic, crystalline powder. It exhibits polymorphism. Slightly soluble in water freely soluble in methyl alcohol soluble in acetone.

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Fluconazole is a triazole antifungal used for superficial mucosal (oropharyngeal, oesophageal, or vaginal) candidiasis and for fungal skin infections. It is also given for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis, and has been tried in blastomycosis, histoplasmosis, and sporotrichosis. The place of fluconazole in the treatment of fungal infections is discussed in the various sections under Choice of Antifungal.

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In general, fewer interactions are considered to occur with fluconazole than with either itraconazole or ketoconazole. Use of rifampicin with fluconazole results in reduced plasma concentrations of fluconazole.

Antifungal Drugs – Targets of Antifungal Activity

Itraconazole is a triazole antifungal drug that is prescribed to patients with fungal infections, blastomycosis, histoplasmosis and onychomycosis. Itraconazole is also prescribed for systemic infections: aspergillosis, candidiasis and cryptococcosis where other antifungal drugs ineffective.

Antifungal Drugs

A number of systemic fungal infections (e.g., histoplasmosis, coccidioidomycosis, and paracoccidioidomycosis) can also afflict otherwise healthy persons. Until recently, only amphotericin B was available to treat systemic fungal infection. However, with the rapid development and clinical assessment of azole compounds, a number of these agents are also considered appropriate for treatment of fungal infections.