Zyvox (Linezolid)

Zyvox
Indications:
infections
Linezolid is an oxazolidinone antibiotic used for certain serious Gram-positive infections (including MRSA and VRE) as prescribed. To get a free extra Zyvox discount coupon, please contact our support team.

Dosages

Zyvox 600 mg

Quantity Price per tablet Total price
30 $7.40 $222.00
60 $7.05 $423.00

Payment & Shipping

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Shipping Times
Shipping MethodEstimated delivery
Express Free for orders over $300.00Estimated delivery to the U.S.: 4-7 days
Standard Free for orders over $200.00Estimated delivery to the U.S.: 14-21 days
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Discount Coupons

  • Independence Day - July 4, 2026 10% JULY410
  • Labor Day - September 7, 2026 7% LABOR07
  • Thanksgiving - November 26, 2026 9% THANKS09

Brand Names

Also known as (by country):
CountryBrand Names
Austria
Zyvoxid
Bangladesh
Arlin
Canada
Zyvoxam
Czechia
Dilizolen
Egypt
Averozolid
France
Zyvoxid
Georgia
Anzolid
Germany
Zyvoxid
India
Linospan Linox Lizolid Lizomac Megazolid
Ireland
Zyvoxid
Italy
Zyvoxid
Kenya
Amizole 500
Netherlands
Dilizolen Grampolid Zyvoxid
Poland
Anozilad Dilizolen Zyvoxid
Portugal
Zyvoxid
Serbia
Anozilad
Slovakia
Dilizolen
Spain
Zyvoxid
Sweden
Zyvoxid
ManufacturerBrand Names
Cipla LimitedLinospan

Description

Note: Images in the description are provided for informational purposes and may differ from the actual appearance of the product. Please refer to the product name, strength, ingredients, and dosage form.

Zyvox (linezolid) is an oxazolidinone antibiotic used to treat certain serious infections caused by susceptible Gram-positive bacteria.

Drug class

Linezolid belongs to the oxazolidinone class of antibiotics.

How it works

Linezolid inhibits bacterial protein synthesis at an early step by preventing formation of the 70S initiation complex.

What Zyvox tablets treat (and what they do not)

Disease / condition (A–Z) Zyvox tablets
Community-acquired pneumonia (CAP)+
Complicated skin and skin structure infections+
Diabetic foot infection (without concomitant osteomyelitis)+
Gonorrhea
Gram-negative infections (e.g., E. coli, Pseudomonas)
Hospital-acquired / nosocomial pneumonia (HAP)+
Osteomyelitis
Pressure ulcers (decubitus ulcers)
Uncomplicated skin and skin structure infections+
Urinary tract infection (UTI)
VRE (Enterococcus faecium) infection, including cases with concurrent bacteremia+
Viral infections (flu/common cold)
Yeast or other fungal infections

Limitations of use (US): Zyvox is not indicated for the treatment of Gram-negative infections. If a Gram-negative pathogen is suspected or confirmed, appropriate therapy should be started.

Indications (US labeling)

Zyvox tablets are used for certain infections caused by susceptible Gram-positive bacteria, including pneumonia (nosocomial and community-acquired), skin and skin structure infections (complicated and uncomplicated), and vancomycin-resistant Enterococcus faecium (VRE) infections, including cases with concurrent bacteremia.

Tablet strength

  • Tablet: 600 mg (film-coated).

Can you split the tablet?

Zyvox 600 mg tablets are film-coated and are not provided as a scored tablet in US labeling. For this reason, splitting or crushing is generally not recommended unless a clinician specifically instructs it.

Zyvox

Why is Zyvox expensive? Are there alternatives?

Cost can be influenced by brand pricing, manufacturing and supply chain factors, and market conditions. Depending on the infection and culture/susceptibility results, clinicians may choose alternatives. FDA-approved generic linezolid tablets are available in the U.S. and may be lower-cost than the brand in some settings.

What medicines is it used with?

Zyvox may be used alone for confirmed susceptible Gram-positive infections. If an infection is mixed or a Gram-negative pathogen is suspected, clinicians may prescribe Zyvox together with other antibiotics that cover Gram-negative organisms (and, when needed, anaerobes). The exact combination depends on the site of infection, severity, and local resistance patterns.

Drug interactions

Linezolid is a reversible, nonselective MAO inhibitor (MAOI). It can interact with adrenergic drugs (which may raise blood pressure) and serotonergic drugs (which may increase the risk of serotonin syndrome). Tell your clinician about all prescription, over-the-counter, and herbal products you use.

Contraindications

Contraindication What it means
Hypersensitivity to linezolid (or any component of the product) Do not use if you have a known serious allergy to linezolid or product ingredients.
Use with MAO inhibitors (or within 2 weeks of stopping an MAOI) Do not use with MAOIs (e.g., phenelzine, isocarboxazid, selegiline) or within 2 weeks of stopping them due to interaction risk.

Tyramine (food interaction)

Because linezolid has MAOI activity, avoid consuming large amounts of tyramine-rich foods and beverages during treatment. Examples include aged cheeses, cured/aged or improperly stored meats, fermented foods (including some soy/yeast products), and certain alcoholic beverages (such as some beers and red wine). Seek medical help if you develop a severe headache, flushing, or a marked rise in blood pressure.

Side effects and key precautions

Common side effects include diarrhea, nausea/vomiting, and headache.

Important warnings and precautions include myelosuppression (including thrombocytopenia; complete blood counts are commonly monitored weekly), peripheral and optic neuropathy (reported mainly with treatment longer than 28 days), lactic acidosis, seizures, and C. difficile-associated diarrhea. Promptly report unusual bruising/bleeding, severe or persistent diarrhea, or new visual symptoms (blurred vision, changes in visual acuity or color vision).

Storage

  • Store at 77°F (25°C); excursions permitted to 59–86°F (15–30°C).
Reviewed by
Donna Brettler
BPharm, MPH - Pharmacologist and medical writer

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