AntiInfectiveMeds
Since 2010
| Quantity | Price per bottle | You save | Total price | |
|---|---|---|---|---|
| 2 | $51.50 | - | $103.00 | |
| 3 | $44.67 | $20.50 | $134.00 | |
| 4 | $44.00 | $30.00 | $176.00 | |
| 5 | $39.80 | $58.50 | $199.00 |
Your order is carefully packed and ships within 24 hours. Here is what a typical package looks like.
Sized like a regular personal letter (9.4x4.3x0.3 inches), with no indication of what is inside.
| Shipping Method | Estimated delivery |
|---|---|
| Express Free for orders over $300.00 | Estimated delivery to the U.S.: 4-7 days |
| Standard Free for orders over $200.00 | Estimated delivery to the U.S.: 14-21 days |
Besivance is a medication used in ophthalmology to treat certain types of bacterial eye infections. The drug was originally developed by a Japanese pharmaceutical company, which later sold the rights to InSite Vision Incorporated. InSite Vision improved the original formulation by developing it as eye drops. In 2003, distribution rights were sold to the American company Bausch + Lomb, one of the world's leaders in ophthalmic medicines and eye-care products.
Six years later, in 2009, the medication received approval from the US Food and Drug Administration (FDA) for the treatment of bacterial conjunctivitis.
The active component of Besivance eye drops is besifloxacin. This drug belongs to the fourth-generation fluoroquinolone antibiotics. It is highly effective against Gram-positive, Gram-negative, and anaerobic bacteria. Therefore, Besivance has a broad spectrum of activity and can be used for eye diseases caused by different types of staphylococci, streptococci, and other besifloxacin-susceptible bacteria.
The mechanism of action is based on inhibition of bacterial DNA gyrase and topoisomerase IV-enzymes responsible for bacterial DNA synthesis and replication. By inhibiting these enzymes, Besivance prevents bacterial growth and leads to bacterial death.
A major benefit of Besivance is that it is specifically designed for ocular use. This helps reduce systemic exposure to the antibiotic and may help limit the development of resistance, which is a key concern in the treatment of bacterial infections.
Besivance is effective against a wide range of bacterial infections that cause inflammation of the eye. It is not effective for infections of viral or fungal origin. Therefore, it's important to have a medical evaluation to identify the pathogen causing the inflammation.
In clinical practice, Besivance may be used in the treatment and prevention of the following ophthalmic diseases and conditions:
Although bacterial infections may also cause other eye diseases, Besivance should not be used for a stye or blepharitis, as its effectiveness for these conditions has not been demonstrated in clinical studies. Moreover, post-marketing reports list blepharitis as a possible adverse effect of Besivance.
These conditions may require combination therapy with antimicrobial agents and corticosteroids to reduce inflammation while targeting the pathogen. One such combination is Tobradex (tobramycin/dexamethasone). Unlike Besivance, Tobradex is used in the treatment of blepharitis.
Pink eye is another name for conjunctivitis. In the United States, this condition affects about 6 million people each year. Pink eye is inflammation of the conjunctiva-a transparent membrane that covers the whites of the eyes and the inner surface of the eyelids. Because of this inflammation, small blood vessels in the conjunctiva become more visible, making the eyes appear pink.
Besivance can help reduce inflammation and eradicate the bacterial pathogen when conjunctivitis is bacterial.
Besivance is supplied as an ophthalmic suspension containing 0.6% besifloxacin. This low concentration of the active ingredient allows topical use. A common question is: "Does Besivance contain aspirin?" This is a misconception; acetylsalicylic acid is not among the active ingredients or excipients.
The dosing regimen and duration of therapy depend on the pathogen causing the infection, the goal of use (treatment or prophylaxis), the severity of the condition, and the patient's response.
To treat bacterial conjunctivitis with Besivance, instill one drop into the affected eye every 6 to 12 hours. There is no need to treat both eyes if only one is infected. Treatment usually lasts 5-8 days. Symptoms may improve sooner (reported in approximately 70% of cases), but this does not mean therapy should be stopped early. By day 5 of treatment, bacterial eradication may reach about 90%. Stopping early can increase the risk of relapse.
In pediatric patients, the dosage generally does not need to be adjusted.
Because the risk of bacterial resistance to Besivance is considered low, it may be used in patients whose ocular infections do not respond to other antibiotics (e.g., ciprofloxacin).
A key recommendation is to maintain sterility of the dropper tip. Be careful each time you open the bottle to avoid contact of the dropper tip with any surface, including your hands and eyes.
After instillation, try to keep your eye closed for 1-2 minutes (with your head tilted back) to allow absorption.
Try not to miss doses to maximize benefit. If you miss a dose of Besivance, instill it as soon as you remember. If it's almost time for the next dose, skip the missed dose.
Because Besivance is used topically, it has few contraindications. One is eye infections caused by viruses or fungi, since the drug is not active against these pathogens.
Besivance should not be used in patients with known hypersensitivity to besifloxacin or other quinolone antibiotics. The product also contains inactive ingredients that may cause allergic reactions in susceptible individuals.
The safety of Besivance in infants younger than 1 year of age has not been established; therefore, it is contraindicated in this age group.
Besivance is available by prescription only; therefore, a doctor's consultation is necessary before starting treatment. To reduce the risk of adverse effects, inform your healthcare provider about all prescription and over-the-counter medicines you are taking.
Besivance may cause adverse reactions that can temporarily affect vision (e.g., blurred vision). Avoid driving or operating machinery until your vision returns to normal.
In pregnancy, Besivance may be used when the potential benefits to the mother outweigh potential risks to the fetus. This caution is based on animal studies in which besifloxacin caused maternal toxicity.
It is not known whether besifloxacin passes into breast milk. If Besivance is necessary during lactation, breastfeeding may need to be discontinued at least for the duration of treatment.
Avoid wearing contact lenses during treatment with Besivance, at least until clinical signs of infection have resolved. Contact lenses may be inserted at least 15 minutes after instilling the drops.
Topical administration generally results in fewer systemic adverse effects. The incidence of the most common side effects ranges from 1% to 10%. If they occur, they usually involve the treated eye (or both eyes, if both are treated):
These reactions usually do not require medical treatment, but you should inform your doctor if they occur, persist, or worsen.
Besivance eye drops are not expected to cause adverse reactions involving the cardiovascular system, liver, or kidneys.
Will my bottle say Besivance, or might it have a different generic or manufacturer name on it?
The exact trade name on the package cannot be guaranteed. When it arrives, verify that the label identifies besifloxacin 0.6% ophthalmic suspension; the manufacturer name and package design may differ.
I live in El Paso. Can I check whether you can ship this to my ZIP code before I place the order?
Yes. Enter your El Paso ZIP code during checkout to see whether this product is available for shipping to your address. Availability is confirmed there rather than assumed for every destination.
I found what looks like the same besifloxacin generic at another online store for about half the price. Why should I order from you instead?
We stand behind the quality of the generic medicines we offer, but we cannot verify what another seller supplies, how it is sourced, handled, or whether its offer is truly equivalent. A similar name and lower price alone do not establish the same manufacturer, origin, handling, or product quality, so the choice is whether the savings are worth that unknown risk to you.
My son is 10 months old and has a red, sticky eye. Is besifloxacin ophthalmic suspension suitable for a baby his age?
Safety and effectiveness of besifloxacin ophthalmic suspension have been established for children age 1 year and older, not for infants younger than 1 year. A 10-month-old with these symptoms should be assessed by a pediatric clinician rather than treated with this medicine on your own.
| Active ingredient | Besifloxacin |
|---|---|
| Drug class | Fluoroquinolone antibiotic |
| Dosage form | Ophthalmic suspension |
| Available strengths | 0.6% |
| Route | Ophthalmic |
| Storage | Store at 59°F to 77°F. Protect from light. |
| ATC code | S01AE09 |
This product has 6 ratings, but only 5 written reviews so far. Share your experience and help other customers.
I'm happy with Besivance's quality.
The package contains 5 units. That size made sense for me.
Good value for Besivance.
A solid product overall.
The packaging was well done.
