Doxycycline

Doxycycline
Generic:
Doxycycline
Indications:
acne amoeba infections malaria
Analogs:
Vibramycin Doryx Monodox Oracea Periostat Minocycline Tetracycline Lymecycline Azithromycin Erythromycin Amoxicillin Mefloquine Cefuroxime Clarithromycin Clindamycin Isotretinoin Levofloxacin
Doxycycline is a tetracycline-class antibiotic available as an oral tablet, and we supply it under the Doxycycline name in 100 mg and 200 mg strengths. Doctors prescribe it for a wide range of bacterial and some protozoal infections, including acne, respiratory infections, certain sexually transmitted infections, and malaria prevention. Because antacids and supplements containing iron, calcium, magnesium, or zinc can reduce doxycycline absorption, timing each dose carefully matters. We offer multiple package quantities for both strengths, and our ordering policy does not require a prescription to accept an order.
In stock: 20 packs
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Doxycycline 100 mg

Quantity Price per tablet You save Total price
10 $3.47 - $34.70
20 $1.93 $30.80 $38.60
30 $1.16 $69.30 $34.80
60 $0.71 $165.80 $42.40
90 $0.55 $262.90 $49.40
120 $0.48 $359.30 $57.10
180 $0.38 $557.10 $67.50
270 $0.33 $848.60 $88.30
360 $0.30 $1,141.90 $107.30

Doxycycline 200 mg

Quantity Price per tablet You save Total price
30 $1.53 - $45.80
60 $1.00 $31.80 $59.80
90 $0.82 $63.50 $73.90
120 $0.73 $95.90 $87.30
180 $0.64 $159.30 $115.50
270 $0.59 $253.90 $158.30
360 $0.56 $349.00 $200.60

Manufacturers

AlphapharmApotex Inc.HexalJourney Medical CorporationLaboratoires BailleulMayne PharmaPfizerPfizer Italia S.r.l.Pierre Fabre Ibérica S.A.Teofarma

Payment & Shipping

Package Example

Your order is carefully packed and ships within 24 hours. Here is what a typical package looks like.

Sized like a regular personal letter (9.4x4.3x0.3 inches), with no indication of what is inside.

Front View
Front View
Side View
Side View
Back View
Back View
Shipping Times
Shipping MethodEstimated delivery
Express Free for orders over $300.00Estimated delivery to the U.S.: 4-7 days
Standard Free for orders over $200.00Estimated delivery to the U.S.: 14-21 days
EMSUSPS
Payment Methods
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Discount Coupons

  • Independence Day - July 4, 2026 10% JULY410
  • Labor Day - September 7, 2026 7% LABOR07
  • Thanksgiving - November 26, 2026 9% THANKS09

Brand Names

Also known as (by country):
CountryBrand Names
United States
Doryx Targadox

FAQ

Take the missed dose when you remember unless it is almost time for the next dose. In that case, skip the missed dose and resume the regular schedule. Do not take two doses together to make up for one missed dose.

Do not save leftover doxycycline for a future illness or give it to another person. Use an authorized medicine take-back program when available, or ask a pharmacist about appropriate local disposal options.

Not necessarily. Tablet color, shape, size, coating, packaging, and imprint can differ from a familiar brand such as Doryx or Targadox. The exact appearance depends on the supplied product, so check the package label for the active ingredient, strength, dosage form, manufacturer, lot number, and expiration date.

Store doxycycline tablets at 68°F to 77°F; brief temperature excursions between 59°F and 86°F are permitted. Keep the container tightly closed and protect it from light and moisture. Keep the medicine out of the reach of children.

Description

Note: Images in the description are provided for informational purposes and may differ from the actual appearance of the product. Please refer to the product name, strength, ingredients, and dosage form.

Why Doxycycline Stands Out When You're Choosing an Oral Antibiotic

Doxycycline has remained a widely used oral antibiotic for decades because it acts against a broad range of susceptible organisms and reaches many body tissues. We carry it specifically as Doxycycline tablets in 100 mg and 200 mg strengths, and that combination of strength options and tablet form is what most readers need to understand before deciding whether it fits an infection, a dermatology plan, or a travel-related malaria prevention schedule. The practical question is not simply whether doxycycline can treat a condition; it is whether this strength, dosage form, and package quantity align with the regimen a prescriber has selected. Antibiotic choice also depends on the likely organism, local resistance patterns, allergies, other medicines, and whether testing or follow-up is needed.

What Doxycycline Is and How It Compares With Vibramycin

The active ingredient in every tablet we sell under this listing is doxycycline, a member of the tetracycline class of antibiotics. We offer oral tablets in 100 mg and 200 mg strengths. The 100 mg strength is available in packages of 10, 20, 30, 60, 90, 120, 180, 270, or 360 pills. The 200 mg strength is available in packages of 30, 60, 90, 120, 180, 270, or 360 pills.

For customers who recognize a branded version of this active ingredient, we also carry Vibramycin. Both products provide doxycycline, but formulation, inactive ingredients, available strengths, and packaging can differ, so they should not be assumed to be interchangeable in every practical detail without checking the specific product. Choosing between Doxycycline and a branded option may involve price and package preference as well as the dosage form a prescriber intended.

Conditions Doxycycline Treats

Doxycycline's broad spectrum explains why prescribers use it across several areas of medicine. Established uses include:

  • Inflammatory acne, where an extended course may reduce susceptible bacteria and inflammation in the skin
  • Respiratory tract infections caused by susceptible organisms, including atypical pneumonia associated with organisms such as Mycoplasma
  • Sexually transmitted infections such as uncomplicated chlamydial infection
  • Tick-borne and rickettsial illnesses, including early Lyme disease and Rocky Mountain spotted fever
  • Periodontal disease in selected regimens used alongside dental treatment
  • Malaria prevention for travelers visiting regions where doxycycline is an appropriate preventive option
  • Acute intestinal amebiasis as an adjunct to an effective amebicide rather than as sole treatment

It is not useful for viral infections such as colds or influenza. A prescriber determines whether doxycycline is appropriate because the dose, course length, testing, and need for companion treatment depend on the condition and the organism involved. For malaria prevention, destination-specific guidance matters because recommendations vary with resistance, itinerary, age, pregnancy status, and other health factors.

How Doxycycline Works and What That Means in Practice

Doxycycline enters susceptible microorganisms and binds to the 30S subunit of the ribosome, interfering with the addition of amino acids to growing proteins. This suppresses the organism's ability to grow and multiply. Its action is usually described as bacteriostatic, so immune defenses continue to play an important role in clearing an infection. Doxycycline also has activity relevant to certain parasites, including malaria parasites, through effects on protein synthesis in susceptible cellular structures.

Good tissue penetration helps explain doxycycline's usefulness in skin, respiratory, tick-borne, and intracellular infections. It does not mean that the medicine covers every bacterial cause, however. Culture results, exposure history, disease severity, and regional resistance can point toward a different antibiotic. Symptoms of many acute susceptible infections begin to improve within a few days, but acne and some inflammatory conditions may require several weeks before a clear benefit appears. Lack of improvement, worsening symptoms, or recurrence should prompt clinical review rather than an unplanned dose increase.

Dosage, Administration, and Daily Timing

Doxycycline dosing is condition-specific. Common adult regimens may use a total of 200 mg on the first day followed by 100 mg daily, 100 mg every 12 hours for more serious infections, or 100 mg once daily for certain preventive uses. Other schedules are used for particular infections and inflammatory conditions. These examples are general information rather than a personal regimen; a prescriber selects the dose and duration, and a 200 mg tablet should not be split unless the specific tablet is designed and labeled for splitting.

Doxycycline can generally be taken with food if it causes stomach upset. It should be swallowed with a full glass of water while sitting or standing, and the patient should remain upright for at least 30 minutes afterward. Taking it immediately before bed increases the chance that a tablet will lodge in the esophagus and cause pain or inflammation.

Practical Timing Choices

SituationWhat to do
Food or milkA light meal, and milk when permitted by the specific product instructions, may help reduce stomach upset; routine separation from ordinary food is not generally necessary
Antacids or mineral supplementsSeparate products containing aluminum, calcium, magnesium, iron, bismuth, or zinc from doxycycline by the interval directed by a clinician or product label, commonly two to three hours
Sun or tanning exposureUse broad-spectrum sunscreen and protective clothing because doxycycline can increase sensitivity to sunlight
A missed doseTake it when remembered unless the next dose is nearly due; skip the missed dose in that case and do not take two doses together

Take the medicine for the duration directed rather than stopping or extending treatment independently. Some infections also require testing after treatment, treatment of close contacts, or temporary avoidance of sexual activity. Those steps are separate from taking the tablets correctly but can be important to preventing reinfection or transmission.

Side Effects, Contraindications, and Drug Interactions

Common side effects include nausea, abdominal discomfort, diarrhea, and increased sensitivity to sunlight. Taking the tablet with enough water and remaining upright reduces the risk of esophageal irritation. Seek prompt medical attention for trouble swallowing, severe or persistent headache, blurred or double vision, a serious rash, facial swelling, difficulty breathing, or severe watery or bloody diarrhea. Intracranial hypertension is uncommon but can threaten vision, while antibiotic-associated colitis can occur during treatment or after it has ended.

  • Doxycycline is contraindicated in anyone with known hypersensitivity to doxycycline or another tetracycline-class medicine such as minocycline or demeclocycline
  • Use during pregnancy requires an individual benefit-risk assessment because exposure during later pregnancy can affect developing teeth and bones
  • Antacids and products containing aluminum, calcium, magnesium, iron, bismuth, or zinc can reduce absorption when taken too close to a dose
  • Warfarin and related anticoagulants may require closer monitoring because the anticoagulant effect can increase
  • Enzyme-inducing medicines such as phenytoin, carbamazepine, and barbiturates can shorten doxycycline's effective exposure
  • Combining doxycycline with isotretinoin is generally avoided because both can increase the risk of intracranial hypertension

Doxycycline is not established as a cause of clinically important oral-contraceptive failure in the way that strong enzyme-inducing drugs are. Vomiting or severe diarrhea can nevertheless interfere with absorption of an oral contraceptive, so patients should follow the contraceptive product's instructions if either occurs. A clinician or pharmacist should review all prescription medicines, nonprescription products, and supplements before treatment begins.

Special Situations: Pregnancy, Children, Older Adults, and Storage

Doxycycline is generally avoided during the latter half of pregnancy because tetracyclines can affect fetal tooth and bone development, although treatment may still be justified when the expected benefit outweighs the risk. People who are pregnant, planning pregnancy, or breastfeeding should discuss the specific indication and course length with a clinician. Tetracyclines can pass into human milk, so the decision to use doxycycline while breastfeeding should be individualized.

Doxycycline has traditionally been avoided in children younger than 8 years because of concern about permanent discoloration of developing teeth and effects on bone growth. For serious infections such as Rocky Mountain spotted fever, anthrax, or another situation in which the benefit outweighs the risk, clinicians may use it in younger children. Pediatric doses are based on the child's weight, age, indication, and disease severity rather than simply using an adult tablet strength.

Older adults can often use standard adult regimens. Doxycycline does not usually require dose adjustment solely because of reduced kidney function, but liver disease, frailty, swallowing difficulty, and interacting medicines may change the monitoring or practical administration plan. Anyone who develops dizziness, vertigo, blurred vision, or double vision should avoid driving or operating machinery until the effect has resolved and has been assessed when appropriate.

Tablets should be stored at 68°F to 77°F, with brief excursions between 59°F and 86°F, in a tightly closed container protected from light and moisture. Do not use outdated or visibly deteriorated tetracycline products, and keep the container out of reach of children.

Ordering Doxycycline Online in the United States

In the United States, oral doxycycline tablets are classified as prescription medication. That classification describes the dosage form's regulatory status and is separate from our process for accepting an order. Under our ordering policy, we do not require a prescription to accept an order for Doxycycline. Customers can buy Doxycycline online through our catalog and choose 100 mg or 200 mg tablets, with the available package quantities shown for the selected strength.

We have operated since 2010, and our pharmacist-supported team is available 24/7 by email, online chat, or phone for questions about an available package or our ordering process. Once an order is placed, we pack and dispatch it for delivery to US addresses. Customers who want to review other medically relevant options can also browse our Antibiotics section, although the appropriate treatment depends on the infection rather than on convenience or apparent similarity between products.

Doxycycline at a Glance

Doxycycline is a versatile, well-established tetracycline antibiotic that we offer as an oral tablet in 100 mg and 200 mg strengths across multiple package quantities. It is used for susceptible bacterial infections, acne, selected tick-borne illnesses, malaria prevention, and certain other condition-specific purposes. Correct use means following the selected regimen, taking each tablet with plenty of water, remaining upright afterward, separating interacting antacids and mineral supplements, and watching for significant sun sensitivity or other adverse effects. Matching the strength and package quantity to the intended course helps avoid interruptions, while our ordering process makes the available options clear for customers in the United States.

Medically reviewed by
Brian Holtry
MD, infectious diseases specialist and medical writer
Updated November 10, 2026

Product specifications

Active ingredientDoxycycline
Drug classTetracycline antibiotic
Dosage formTablet
Available strengths100 mg, 200 mg
Route of administrationOral
StorageStore at 68°F to 77°F; brief excursions permitted between 59°F and 86°F. Keep in a tightly closed container, protected from light and moisture.
ATC codeJ01AA02

Regulatory information

Approval statusDoxycycline is approved for human use in the United States.
Prescription statusA valid prescription from a licensed healthcare provider is required to obtain doxycycline tablets.

More information