Anidulafungin is an echinocandin antifungal active against Aspergillus and Candida spp. It is used in the treatment of candidaemia, oesophageal candidiasis, and other forms of invasive candidiasis.


Amorolfine is a morpholine derivative with antifungal activity. It appears to act by interfering with the synthesis of sterols essential for the functioning of fungal cell membranes. Amorolfine is active in vitro against a wide variety of pathogenic and opportunistic fungi including dermato-phytes, Blastomyces ckrmatitidis, Candida spp., Histoplasma capsulatum, and Sporothrix schenckii. It also has variable activity against Aspergillus spp.

Amphotericin B

Amphotericin B is active against Absidia spp., Aspergillus spp., Basidiobolus spp., Blastomyces dermatitidis, Candida spp., Coccidioides immitis, Conidiobolus spp., Cryptococcus neoformans, Histoplasma capsulatum, Mucor spp., Paracoccidioides brasiliensis, Rhizopus spp., Rhodotorula spp., and Sporothrix schenckii.


Amprenavir is an HIV-protease inhibitor with antiviral activity against HIV. ft is used in the treatment of HIV infection and AIDS. Viral resistance emerges rapidly when amprenavir is used alone, and it is therefore used with other antiretrovirals.


Adefovir is converted intracellularly in stages to the di-phosphate, which then inhibits the DNA synthesis of hepatitis B virus through competitive inhibition of reverse transcriptase and incorporation into viral DNA. At high doses it has some activity against HIV.

Order Acyclovir (Zovirax) No Prescription 200/400/800mg

Acyclovir is active against herpes simplex virus type 1 and type 2 and against varicella-zoster virus. This activity requires intracellular conversion of aciclovir by viral thymidine kinase to the monophosphate with subsequent conversion by cellular enzymes to the diphosphate and the active triphosphate.


Abacavir is converted intracellularly in stages to its active form carbovir triphosphate. This halts the DNA synthesis of retroviruses, including HIV, through competitive inhibition of reverse transcriptase and incorporation into viral DNA.

Case: Antibacterial agents. Questions – Answers

Which of the following is the most likely explanation for multiple drug resistance to antibiotics that spreads from one type of bacteria to another? Penicillins inhibit which of the following bacterial processes/ compounds? Ototoxicity and nephrotoxicity are characteristic adverse effects of which of the following?