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Nalidixic Acid is authorised in the world under the following brand names: Cybis, Dixiben, Dixinal, Eucistin, Innoxalon, Jicsron, naladixic acid, Nalidic acid, Nalidixan, Nalidixate, Nalidixic acid USP27, Nalidixin, Nalidixinic acid, Nalitucsan, Nalix, Nalurin, Naxuril, NegGram, Negram, Nevigramon, Nogram, Sicmylon, Unaserus, Urisal, Uronidix, Wintomylon, Wintron.

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Nalidixic acid, the first quinolone, first introduced in 1962, is now only rarely used and has been supplanted by the fluoroquinolones. It is almost completely absorbed from the gastrointestinal tract and is rapidly eliminated by the kidneys, resulting in urinary concentrations 4-6 times higher than plasma concentrations.

Antimicrobial therapy: general principles

A wide variety of antimicrobial agents is available to treat established infections caused by bacteria, fungi, viruses, or parasites. This section will cover the general principles of antimicrobial therapy and will also include illustrative clinical problems to emphasize proper decision-making in using antimicrobials.

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An almost white or pale yellow, crystalline powder. Practically insoluble in water; slightly soluble in alcohol and in acetone; soluble in dichloromethane. It dissolves in dilute solutions of alkali hydroxides. Store in airtight containers.

Dosage forms of Nalidixic Acid:
Nalidixic acid powder

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Therapeutic classes of Nalidixic Acid:

Anti-Infective Agents, Enzyme Inhibitors, Nucleic Acid Synthesis Inhibitors


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