Zovirax cream (Aciclovir)

Zovirax cream
4.77 ratingsReviews
Generic:
Aciclovir
Analogs:
Aciclovir Valaciclovir Famciclovir Penciclovir Docosanol Abreva Denavir Vectavir Valtrex Famvir
Zovirax cream is available over the counter in our store. You can order 5 g tubes online today. The 2 g and 10 g tube sizes, as well as a pump dispenser, will be added to our catalog shortly. Zovirax Duo and Zovirax Intensive are also expected back in stock in the near future.
In stock: 12 packs
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Zovirax cream 5 g

Quantity Price per tube You save Total price
2 $24.50 - $49.00
3 $20.20 $12.90 $60.60
4 $17.98 $26.10 $71.90
5 $16.96 $37.70 $84.80
6 $16.17 $50.00 $97.00
7 $15.49 $63.10 $108.40
8 $15.11 $75.10 $120.90
9 $14.82 $87.10 $133.40
10 $14.51 $99.90 $145.10

Manufacturers

GlaxoSmithKlineHaleon

Payment & Shipping

Package Example

Your order is carefully packed and ships within 24 hours. Here is what a typical package looks like.

Sized like a regular personal letter (9.4x4.3x0.3 inches), with no indication of what is inside.

Front View
Front View
Side View
Side View
Back View
Back View
Shipping Times
Shipping MethodEstimated delivery
Express Free for orders over $300.00Estimated delivery to the U.S.: 4-7 days
Standard Free for orders over $200.00Estimated delivery to the U.S.: 14-21 days
EMSUSPS
Payment Methods
VisaMastercardAmerican ExpressDiscoverBitcoin, USDTApple PayGoogle PayPayPal

Discount Coupons

  • Independence Day - July 4, 2026 10% JULY410
  • Labor Day - September 7, 2026 7% LABOR07
  • Thanksgiving - November 26, 2026 9% THANKS09

FAQ

In the United States, aciclovir cream requires a prescription when purchased from local pharmacies. Our store policy allows you to order it without a prescription and have it sent by mail. Our store ordering policy is separate from the product's prescription-only classification in the United States.

Apply the missed application when you remember, unless it is nearly time for the next one. Then continue with the regular schedule. Do not apply an extra amount to make up for a missed application.

The manufacturer of the supplied product may vary. The manufacturer's name is shown on the product packaging.

This product is available as aciclovir 5% cream. It is supplied in tubes.

During pregnancy, use aciclovir cream only after a clinician has weighed the potential benefit against potential fetal risk. Systemic absorption from skin application is low, but the decision still needs individual assessment. During breastfeeding, use caution because it is not known whether topically applied aciclovir passes into human milk; avoid applying cream where an infant could directly ingest it.

Zovirax cream contains the antiviral aciclovir and is used for recurrent herpes labialis, commonly called cold sores, in immunocompetent adults and adolescents age 12 and older. It works locally on the cold sore and should be started as early as possible when symptoms or lesions first appear.

Description

Note: Images in the description are provided for informational purposes and may differ from the actual appearance of the product. Please refer to the product name, strength, ingredients, and dosage form.

Zovirax (Acyclovir) Cream: Key Facts

  • Used for recurrent herpes labialis (cold sores) on the lips/face caused by herpes simplex virus (HSV).
  • For immunocompetent adults and adolescents 12 years and older.
  • Apply only to the external lips/face. Do not use in the eyes, inside the mouth or nose.

Zovirax (Acyclovir) Cream 2 g

What It Treats

Zovirax cream contains acyclovir and is indicated for treating recurrent herpes labialis (cold sores) when applied early in an outbreak.

Zovirax for Cold Sores vs Genital Herpes

Condition Can Zovirax (acyclovir) cream be used? Notes
Cold sores on the lips/face (recurrent herpes labialis) Yes (on-label) Start early (tingling/itching) or when lesions appear.
Genital herpes No Zovirax cream is not intended for use on the genitals. Genital herpes is typically treated with prescription oral antivirals based on clinician advice.

What Zovirax Cream Does Not Do

  • It does not cure herpes (HSV remains in the body).
  • It does not prevent future outbreaks.
  • It does not stop transmission to other people.

Before You Use

  • Do not use if you have an allergy to acyclovir, valacyclovir, or any component of the formulation.
  • Children under 12 years: safety and effectiveness have not been established. Use only if your healthcare provider tells you to.

If you are pregnant, planning to become pregnant, or breastfeeding, talk to your healthcare provider before using this medicine.

This product contains propylene glycol and cetostearyl alcohol, which may cause local skin reactions such as stinging or burning. If you have a known intolerance to these substances, ask a healthcare professional before use.

How to Use

Question Answer
How much should I apply? Apply a thin layer in a sufficient quantity to fully cover the affected area.
When should I start? As early as possible at the first sign of an outbreak (tingling/itching) or when lesions appear.
How often? 5 times per day.
How long? 4 days. If not healed, you may continue up to 10 days; see a healthcare provider if symptoms persist beyond that.
How quickly does it work? It may shorten the episode when started early, but it is not a cure and results vary from person to person.

Missed dose: apply as soon as you remember. If it is nearly time for the next application, skip the missed dose and continue your regular schedule.

If you apply too much: topical overdosage is unlikely. If irritation occurs, wash the area gently and consult a healthcare provider.

Zovirax Cream vs Acyclovir Ointment (5%)

Feature Zovirax (acyclovir) Cream 5% Acyclovir Ointment 5%
Main on-label use Recurrent herpes labialis (cold sores) on lips/face (≥12 years) Initial genital herpes; limited mucocutaneous HSV in immunocompromised patients (prescription use)
Where to apply External lips/face only; not in eyes, mouth, or nose Cutaneous use only; not in the eye (genital use may be prescribed for initial genital herpes per label)
Typical dosing 5 times per day for 4 days (up to 10 days if needed) Every 3 hours, 6 times per day for 7 days

Possible Side Effects

  • Mild pain, burning, or stinging at the application site.
  • Dry, flaky skin or cracked lips.
  • Itching or redness in the treated area.

Rarely: severe allergic reactions (e.g., swelling of the face/lips/throat, trouble breathing) or allergic skin reactions such as contact dermatitis or eczema. Stop using the cream and seek medical advice if this happens.

Storing and Expiration Date

  • Keep out of the reach and sight of children.
  • Store at or below 77°F (25°C); excursions permitted to 59°F to 86°F (15°C to 30°C).
  • Store in the original package.
  • Do not use after the expiration date shown on the carton/tube. If expired, stop using it and dispose of it properly (ask your pharmacist for advice).

Further Information

The active ingredient is acyclovir 5% w/w (50 mg per gram of cream).

The other ingredients are cetostearyl alcohol, mineral oil, poloxamer 407, propylene glycol, sodium lauryl sulfate, water, and white petrolatum.

Zovirax cream is a smooth white to off-white cream. Packaging may vary by market; in the US, ZOVIRAX Cream is supplied in 5 g tubes.

Health and Hygiene

Cold sores are small, fluid-filled blisters that typically appear on or around the lips and are caused by HSV. To help reduce spread during an outbreak:

  • Avoid close contact with others.
  • Do not share items that may have contacted the sore (e.g., utensils, towels, lip balm).
  • Wash hands frequently, especially after touching the affected area.
  • Avoid picking at blisters to help prevent secondary infection.
Medically reviewed by
Brian Holtry
MD, infectious diseases specialist and medical writer
Updated August 11, 2026

Customer questions

Asked by William K, Austin, United States

My Zovirax cream arrived in Austin and the tube seal looks partly broken. Can I still use it?

Answered by Support team

No. Do not use cream if the seal or tube condition appears compromised until the discrepancy has been checked. Keep the packaging and tube available when requesting assistance with the order.

Asked by Michael Rivera, Phoenix, United States

I receive my mail at a PO Box in Phoenix. Can I use that address for this order?

Answered by Support team

For a Phoenix PO Box, enter the address during checkout and use it only if it is accepted in the available address options. We cannot confirm PO Box eligibility before checkout.

Asked by Lauren Mitchell, San Antonio, United States

I only use cold sore cream occasionally. Will the tube have a certain amount of shelf life remaining when it arrives?

Answered by Support team

We cannot guarantee a specific remaining shelf life before an order is shipped. The exact expiration date is printed on the tube and its packaging; do not use the cream after that date.

Asked by Jacob G, San Jose, United States

I live in San Jose, where summer deliveries can sit in the sun. Can this cream normally travel through the mail?

Answered by Support team

A sealed cream tube can normally be mailed when it is appropriately protected from damage and handled according to its labeled storage conditions. Store it at 77°F, with permitted excursions from 59°F to 86°F, keep the tube tightly closed, and do not freeze it. Inspect the tube and seal on arrival, and do not use it if heat exposure or physical condition is concerning.

Asked by Jessica Nguyen, San Francisco, United States

I felt mild stinging and dryness where I applied the cream for a cold sore. Is that a side effect?

Answered by Support team
Medical reviewed by Brian Holtry

Mild temporary burning, stinging, dryness, flaking, or irritation at the application site can occur with aciclovir cream. Stop using it and seek prompt medical help for signs of an allergic reaction, such as widespread rash, marked swelling, hives, or trouble breathing.

Product specifications

Active ingredientAciclovir
Drug classAntiviral
Dosage formCream
Available strengths5%
RouteTopical
StorageStore at 77°F; excursions permitted to 59°F - 86°F. Keep the tube tightly closed and do not freeze.
ATC codeD06BB03

Regulatory information

Approval statusAciclovir is approved for human medical use in the United States.
Prescription requirementThis topical cream requires a valid prescription from a licensed healthcare provider.

More information