Tenvir (Tenofovir Disoproxil)

Tenvir
4.77 ratingsReviews
Generic:
Tenofovir Disoproxil
Analogs:
Viread Truvada Vemlidy Baraclude Biktarvy Triumeq Descovy Tenof Entecavir Epivir Lamivudine Hepsera Ziagen Abacavir
Multi-use discount coupon for Tenvir (Tenofovir Disoproxil Fumarate): TDF2026. Valid through December 31, 2026, and gives 10% off.
In stock: 16 packs
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Tenvir 300 mg

Quantity Price per tablet You save Total price
30 $4.73 - $142.00
60 $4.38 $21.00 $263.00
90 $4.19 $49.00 $377.00

Manufacturers

Gilead Sciences

Payment & Shipping

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Shipping Times
Shipping MethodEstimated delivery
Express Free for orders over $300.00Estimated delivery to the U.S.: 4-7 days
Standard Free for orders over $200.00Estimated delivery to the U.S.: 14-21 days
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Discount Coupons

  • Independence Day - July 4, 2026 10% JULY410
  • Labor Day - September 7, 2026 7% LABOR07
  • Thanksgiving - November 26, 2026 9% THANKS09

Brand Names

Also known as (by country):
CountryBrand Names
United States
Viread

FAQ

Yes. Tell the surgeon, dentist, anesthesiologist, or other procedure provider that you take tenofovir disoproxil and provide a complete list of medicines and supplements. Do not stop or change this medicine on your own before a procedure; the care team should decide whether any treatment changes are needed.

The manufacturer of the supplied product may vary. The manufacturer's name is shown on the product packaging.

Compare the package label with the order details: it should identify tenofovir disoproxil, 300 mg, and tablets for oral use. Also check the manufacturer, lot number, expiration date, and tablet imprint if one is present. Do not take the tablets until any difference in ingredient, strength, dosage form, seal, or physical condition has been checked.

Store the tablets below 86°F in a dry place, protected from moisture, and keep them in the original container. Keep the container closed and out of reach of children.

Tenofovir disoproxil 300 mg tablets are taken by mouth and may be taken with or without food, preferably at the same time each day. The standard adult regimen is often 300 mg once daily, but the prescribed regimen depends on the condition being treated, kidney function, age, weight, and other medicines. For HIV, tenofovir disoproxil is used with other antiretroviral medicines rather than alone.

Tenofovir disoproxil is an antiviral medicine used with other antiretroviral drugs to treat HIV-1 infection and is also used to treat chronic hepatitis B. It helps suppress viral replication but does not cure HIV or hepatitis B.

Description

Note: Images in the description are provided for informational purposes and may differ from the actual appearance of the product. Please refer to the product name, strength, ingredients, and dosage form.

TDF and CHB

WHO estimates that about 254 million people were living with chronic hepatitis B (CHB) in 2022. Chronic HBV infection can lead to long-term complications such as cirrhosis, liver failure, and an increased risk of hepatocellular carcinoma (HCC). Over the last decade, HBV management has improved, and effective antiviral therapy options include tenofovir disoproxil fumarate (TDF).

TDF is an orally administered pro-drug of tenofovir, a nucleotide reverse transcriptase inhibitor active against both hepatitis B virus (HBV) and HIV-1. For HIV-1, TDF is used only in combination with other antiretroviral agents. For chronic hepatitis B, TDF is used as an antiviral therapy option; patients should be tested for HIV-1 before starting TDF for HBV.

Tenofovir Disoproxil Fumarate

Clinical trial data support that TDF can help suppress HBV DNA in many patients during long-term therapy. In adult trials, continued follow-up included long-term treatment up to 384 weeks in extension phases. In the treatment of chronic hepatitis B, the optimal duration of treatment is unknown.

Important safety note: severe acute exacerbations of hepatitis B have been reported after discontinuation of anti-hepatitis B therapy, including TDF. Hepatic function should be monitored with clinical and laboratory follow-up for at least several months after stopping therapy; if appropriate, resumption of treatment may be warranted.

Indications

VIREAD (tenofovir disoproxil fumarate, TDF) is indicated for the treatment of chronic hepatitis B virus (HBV) in adults and pediatric patients 2 years of age and older weighing at least 10 kg.

Drug interactions

TDF is primarily eliminated by the kidneys. Coadministration with drugs that are eliminated by active tubular secretion may increase concentrations of tenofovir and/or the coadministered drug; drugs that decrease renal function may increase tenofovir concentrations. In the treatment of chronic hepatitis B, TDF should not be administered in combination with adefovir dipivoxil.

  • Coadministration decreases atazanavir concentrations. When coadministered with TDF, use atazanavir given with ritonavir. Certain HIV-1 protease inhibitors (including lopinavir/ritonavir) and some HCV regimens can increase tenofovir concentrations-monitor for evidence of tenofovir toxicity (including renal adverse reactions).
  • TDF increases didanosine concentrations. Dose reduction and close monitoring for didanosine toxicity are warranted.
  • Examples of drugs eliminated by active tubular secretion include acyclovir, cidofovir, ganciclovir, valacyclovir, valganciclovir, aminoglycosides (e.g., gentamicin), and high-dose or multiple NSAIDs. If coadministered, monitor renal function as clinically appropriate.

Possible side effects

Along with its desired action, this medicine may cause unwanted effects. Evaluation of adverse reactions in CHB with compensated liver disease is based on controlled clinical trials in 641 subjects who received treatment during a 48-week double-blind period.

In these trials, the most common adverse reaction (all grades) was nausea (9%). Other treatment-emergent adverse reactions reported in more than 5% of subjects included abdominal pain, diarrhea, headache, dizziness, fatigue, nasopharyngitis, back pain, and skin rash.

It should be noted that stopping therapy can lead to a flare (worsening) of hepatitis B. During follow-up after discontinuation, monitor liver function with clinical and laboratory parameters for at least several months. If appropriate, it may be advisable to resume treatment.

Storage

Store TDF tablets at 77°F (25°C); excursions permitted to 59-86°F (15-30°C) (USP Controlled Room Temperature). Keep the bottle tightly closed and dispense only in the original container. Do not use if the seal over the bottle opening is broken or missing. Keep out of reach of children.

Medically reviewed by
Brian Holtry
MD, infectious diseases specialist and medical writer
Updated August 11, 2026

Customer questions

Asked by Melissa L, Phoenix, United States

I found what appears to be the same tenofovir product at another online store for about half the price. Why should I order from you instead?

Answered by Support team

We stand behind the quality of the products we offer. We cannot verify what another seller supplies, how it is sourced or handled, or whether a similarly named, lower-priced offer is truly equivalent in manufacturer, origin, and product quality. The choice is yours, but only you can decide whether the savings are worth accepting that uncertainty.

Asked by Danielle, San Diego, United States

I take tenofovir disoproxil for chronic hepatitis B and just found out that I am pregnant. Is it safe to keep taking it?

Answered by Support team
Medical reviewed by Donna Brettler

Tenofovir disoproxil is an established treatment option during pregnancy, and available human data have not shown an increased overall risk of major birth defects. Contact the clinician managing your hepatitis B promptly to review your treatment, but do not stop it on your own because stopping antiviral therapy can lead to a hepatitis B flare.

Product specifications

Active ingredientTenofovir disoproxil
Drug classNucleotide reverse transcriptase inhibitor (NtRTI)
Dosage formTablet
Available strengths300 mg
RouteOral
StorageStore below 86°F in a dry place, protected from moisture, in the original container.
ATC codeJ05AF07

Regulatory information

Approval StatusTenofovir disoproxil is officially approved for human medical use in the United States.
Prescription RequirementTenofovir disoproxil oral tablets require a valid prescription from a licensed healthcare provider.

More information