Lotrisone cream (Clotrimazole and Betamethasone)

Lotrisone cream
4.77 ratingsReviews
Generic:
Clotrimazole and Betamethasone
Analogs:
Clotrimazole Terbinafine Miconazole Econazole Ketoconazole Daktacort Travocort Lotriderm Nystatin And Triamcinolone
Buy Lotrisone cream (clotrimazole 1% / betamethasone 0.05%) online over the counter. Commonly used for certain fungal skin infections such as ringworm (tinea) and for relieving associated itching and inflammation.
In stock: 17 packs
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Lotrisone cream 10 g

Quantity Price per tube You save Total price
5 $3.48 - $17.40
6 $3.10 $2.28 $18.60
7 $2.87 $4.26 $20.10
8 $2.64 $6.74 $21.10
9 $2.72 $6.82 $24.50
10 $2.58 $9.00 $25.80

Lotrisone cream 20 g

Quantity Price per tube You save Total price
2 $8.95 - $17.90
4 $7.30 $6.60 $29.20
8 $6.76 $17.50 $54.10
16 $6.53 $38.80 $104.40

Manufacturers

Organon CanadaOrganon Healthcare GmbHOrganon LLC

Payment & Shipping

Package Example

Your order is carefully packed and ships within 24 hours. Here is what a typical package looks like.

Sized like a regular personal letter (9.4x4.3x0.3 inches), with no indication of what is inside.

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Front View
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Back View
Back View
Shipping Times
Shipping MethodEstimated delivery
Express Free for orders over $300.00Estimated delivery to the U.S.: 4-7 days
Standard Free for orders over $200.00Estimated delivery to the U.S.: 14-21 days
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Discount Coupons

  • Independence Day - July 4, 2026 10% JULY410
  • Labor Day - September 7, 2026 7% LABOR07
  • Thanksgiving - November 26, 2026 9% THANKS09

Brand Names

Also known as (by country):
CountryBrand Names
United States
Lotrisone

FAQ

In the United States, clotrimazole and betamethasone cream requires a prescription when purchased from local pharmacies. Our store policy allows you to order it without a prescription and have it sent by mail.

Do not use the cream if the tube is punctured, leaking, visibly damaged, or if its protective closure appears compromised. Keep the package and have the product condition checked before using it.

Not necessarily. The tube design, cream appearance, package labeling, and inactive ingredients can differ between manufacturers, and a brand reference does not identify the exact product supplied. Verify the active ingredients, strength, dosage form, and package label when the order arrives.

Check the tube and outer package for clotrimazole 1% and betamethasone dipropionate 0.05%, and confirm that the dosage form is cream. Also compare the manufacturer name, lot number, and expiration date on the package; do not use the product if the ingredient, strength, or dosage form is different from what was ordered.

Store the cream between 36°F and 86°F, and do not freeze it. Keep it away from excessive heat and check the tube and cream before use if storage conditions may have been exceeded.

This cream is used for inflammatory fungal skin infections caused by susceptible dermatophytes, including athlete's foot, jock itch, and ringworm of the body. Clotrimazole treats the fungus, while betamethasone helps reduce associated redness, itching, and inflammation. It is not intended for every type of rash or skin infection.

Apply a thin layer to clean, dry affected skin and a small amount of surrounding skin, usually twice daily. Standard treatment is commonly 2 weeks for jock itch or ringworm of the body and up to 4 weeks for athlete's foot, but the prescribed directions take priority. Wash hands after application, and avoid the eyes, face, underarms, occlusive dressings, and diaper areas.

During pregnancy, use requires a clinician's assessment because the cream contains a potent topical corticosteroid and human pregnancy data are limited. During breastfeeding, use caution and do not apply the cream to the nipple or areola, where an infant could ingest it. If treatment is needed, exposure is generally minimized by using the smallest amount for the shortest appropriate time.

Description

Note: Images in the description are provided for informational purposes and may differ from the actual appearance of the product. Please refer to the product name, strength, ingredients, and dosage form.

Containing two active ingredients, Lotrisone can help manage certain inflammatory fungal infections of the skin. Clotrimazole helps control fungal growth, while betamethasone (a corticosteroid) reduces redness, itching, and inflammation in the affected area.

When do you need Lotrisone?

Lotrisone may be used for certain fungal skin infections. To determine which organism is causing your symptoms, you should consult a clinician. You may also need tests to identify the pathogen.

For yeast-related skin infections, Lotrisone may be used only when the skin is affected. It should not be used for vaginal yeast infections or on mucous membranes. A typical course may last up to 2 weeks with twice-daily application, depending on the condition and your clinician’s advice.

The preparation is commonly prescribed for ringworm, jock itch, and athlete’s foot.

Can Lotrisone be used for eczema?

No. Eczema is not a fungal infection, so Lotrisone is not appropriate and may be harmful if used incorrectly.

Dosage and instructions for use

Lotrisone is available as a cream or lotion. Both typically contain clotrimazole 1% and betamethasone 0.05% (the same active ingredients), so you and your healthcare provider can decide which formulation is best.

The duration of therapy may vary depending on your progress and the condition being treated. For ringworm, Lotrisone is often used twice daily for at least 1 week. Even if symptoms improve sooner, complete the course as directed to reduce the risk of recurrence.

Lotrisone cream

If symptoms are still present after 1 week, treatment may be continued for another 7 days, depending on clinical advice. A similar approach may be used for jock itch. When treating a fungal infection in the groin, make sure underwear is not tight and is made of natural fabrics to reduce sweating and moisture.

Athlete’s foot can be harder to treat and may require up to 4 weeks. The cream or lotion is usually applied twice a day (in the morning and at bedtime).

Rub the medicine gently into the affected areas of the skin.

Can Lotrisone be used on the face?

Use on the face only if specifically advised by a clinician. Avoid getting the cream or lotion into the eyes, nose, or mouth.

Do not use more than 45 g of cream or 45 mL of lotion per week unless directed by a clinician, as excessive use can increase the risk of side effects.

Who shouldn’t use Lotrisone?

Certain patients should avoid Lotrisone. This includes people with:

  • Known hypersensitivity to clotrimazole, betamethasone, or any inactive component of the medication;
  • Melanoma;
  • Skin cancer;
  • Hemangioma or other skin tumors;
  • Circulation problems;
  • Immunosuppression/low immunity.

Lotrisone is contraindicated in individuals younger than 17 years. Older adults should use the preparation under close supervision, as the risk of side effects may be higher. Never use this medicine orally or vaginally. Avoid getting it into the eyes and nose.

During pregnancy, Lotrisone should be used only if the potential benefits outweigh the risks and if advised by a clinician. If you are breastfeeding, consult a healthcare professional before use.

What unwanted reactions may occur?

The remedy is usually well tolerated when used as directed. However, side effects can occur. The most common local reactions include:

  • Dry skin;
  • Itching and redness;
  • Peeling;
  • Burning;
  • Rash.

These reactions are typically limited to the areas where the medication is applied. If you experience these symptoms, contact your clinician to discuss next steps.

Rare but potentially serious effects have also been reported. Seek medical advice promptly if you notice:

  • Fever;
  • Difficulty urinating;
  • Skin discoloration or thinning;
  • Stretch marks or acne-like eruptions;
  • Headache;
  • Nausea or vomiting.

This is not a complete list of possible reactions. Ask a pharmacist or clinician for more information, and seek urgent medical help for severe or concerning symptoms.

Medically reviewed by
Brian Holtry
MD, infectious diseases specialist and medical writer
Updated August 11, 2026

Customer questions

Asked by Megan Carter, Columbus, United States

Will the Lotrisone cream package include instructions in English?

Answered by Support team

The leaflet language for the specific package is not guaranteed. Please check the received tube and package labeling for the directions and warnings before use; the active ingredients, strength, and cream dosage form should also be listed there.

Asked by Daniel Reyes, Fort Worth, United States

I may need to reorder later. Will my next tube come from the same manufacturer?

Answered by Support team

We cannot guarantee that a future order will come from the same manufacturer. Check each received package for the active ingredients, clotrimazole 1% and betamethasone dipropionate 0.05%, the cream dosage form, strength, manufacturer, lot number, and expiration date.

Asked by Patricia Nguyen, Los Angeles, United States

I have type 2 diabetes and use insulin. Can the betamethasone in this cream affect my blood sugar?

Answered by Support team
Medical reviewed by Brian Holtry

It can, although this is less likely with short-term use on a small area. Applying the cream over large areas, for a long time, or under a covering can increase corticosteroid absorption and may raise blood sugar, so discuss those circumstances with the clinician managing your diabetes.

Product specifications

Active ingredientClotrimazole and betamethasone
Drug classTopical antifungal and corticosteroid combination
Dosage formCream
Available strengthsClotrimazole 1% / betamethasone dipropionate 0.05%
RouteTopical
StorageStore between 36°F and 86°F; do not freeze.
ATC codeD01AC20

Regulatory information

Market AuthorizationThe combination of clotrimazole and betamethasone is authorized by the FDA for human therapeutic use in the United States.
Prescription StatusClotrimazole and betamethasone cream is a prescription-only medication that requires an order from a licensed healthcare provider.

More information