AntiInfectiveMeds
Since 2010
| Quantity | Price per tube | You save | Total price | |
|---|---|---|---|---|
| 1 | $67.00 | - | $67.00 | |
| 3 | $45.00 | $66.00 | $135.00 | |
| 6 | $36.00 | $186.00 | $216.00 |
Your order is carefully packed and ships within 24 hours. Here is what a typical package looks like.
Sized like a regular personal letter (9.4x4.3x0.3 inches), with no indication of what is inside.
| Shipping Method | Estimated delivery |
|---|---|
| Express Free for orders over $300.00 | Estimated delivery to the U.S.: 4-7 days |
| Standard Free for orders over $200.00 | Estimated delivery to the U.S.: 14-21 days |
| Country | Brand Names |
|---|---|
| United States | Lamisil AT |
Lamisil cream represents an innovative approach to the topical treatment of diverse infections and diseases of the skin and subcutaneous tissues. This product is characterized by high effectiveness in most patients, great tolerability, a low rate of reported side effects, and gentle curative action. The main active ingredient of the cream is terbinafine. This chemical substance belongs to the group of allylamines and has a wide range of antifungal effects. Even comparatively low concentrations of this active ingredient provide a significant fungicidal effect on most dermatophytes and dimorphic fungi.
Lamisil formulations contain terbinafine hydrochloride at a concentration of 1% w/w for topical applications, such as creams or gels. One gram of the cream contains terbinafine hydrochloride 10 mg, equal to 8.8 mg of terbinafine. Additional excipients may include cetyl alcohol, stearyl alcohol, and benzyl alcohol, which contribute to the texture and stability of the product.
Terbinafine works by inhibiting squalene epoxidase, an enzyme crucial for ergosterol synthesis in fungal cell membranes, leading to cell death and effective treatment of infections like athlete's foot and onychomycosis. Less than 5% of the dose is absorbed after drug administration on the affected skin area. Therefore, the absorption of terbinafine into the systemic circulation is negligible.
The effect provided by the drug may be fungicidal and fungistatic. The drug has a long-lasting effect, which allows patients not only to achieve a desirable effect after using Lamisil cream but also to prevent recontamination after a short period of treatment.
Lamisil (Terbinafine) is indicated for the topical treatment of the following dermatologic infections: tinea (pityriasis) versicolor due to Malassezia furfur (formerly Pityrosporum ovale), tinea pedis (athlete's foot), tinea corporis (ringworm), or tinea cruris (jock itch) due to Trichophyton rubrum, Trichophyton mentagrophytes, or Epidermophyton floccosum. Diagnosis of disease should be confirmed either by culture (except Malassezia furfur, formerly Pityrosporum ovale) or examination of scrapings from infected tissue mounted in a solution of potassium hydroxide.
Terbinafine specifically inhibits the early stage of the biosynthesis of sterols in fungal cell membranes. This effect leads to the deficiency of ergosterol and intracellular accumulation of squalene, which causes the death of fungal cells. Terbinafine acts by inhibiting the squalene epoxidase enzyme in the cell membrane. Since this enzyme does not belong to the cytochrome P450 system, terbinafine does not affect the metabolic pathways of hormones in the human body.
Lamisil cream is used to treat various fungal skin infections: tinea pedis (athlete's foot), tinea cruris (jock itch), and tinea corporis (ringworm).
For adults and children 12 years and older, Lamisil cream should be applied 1-2 times per day depending on the observed severity of the infection.
The duration of treatment depends on the severity of the disease.
Elderly patients do not require additional dose adjustments. As for the pediatric population, the clinical experience of using the drug in children under 12 years of age is limited, so the drug should not be used to treat this age category of patients.
The cream should be applied to the affected area and surrounding skin after cleaning and drying the area thoroughly. It is essential to avoid contact with the eyes, nose, mouth, and other mucous membranes. If irritation occurs, use should be discontinued. Consistent application as directed is crucial for effective treatment, even if symptoms begin to improve before the entire course is completed.
The drug also shows very efficient results in the therapy of yeast infections. Lamisil cream for penile yeast infection therapy has better results than therapy with most currently prescribed antiseptic agents. The active components of the drug penetrate deeply into the affected penile tissues and make it possible to cure the disease starting from the inner cellular layers. However, these active ingredients also perfectly fulfill their external functions, eliminating pus cells from the tissue, i.e., cleansing the affected area of the external irritant.
Lamisil cream for yeast diaper rash should be administered four times per day. If the positive effects are not observed after three days, you should inform your healthcare provider to find an adequate replacement or adjust the daily dose.
Lamisil is not for ophthalmic, oral, or intravaginal use. The cream is intended for external use only. The patient should be told to use Lamisil as directed by the physician.
The notable signs of relief are usually observed two to three days after the beginning of therapy. Irregular use or premature discontinuation of treatment may lead to reactivation of the infection.
If the signs of any notable improvement are not observed after two weeks of treatment, you should contact your doctor. Additional dose adjustments may be necessary.
Lamisil (Terbinafine) is contraindicated in individuals with known or suspected hypersensitivity to terbinafine or any other of its components. Inform the physician if the application area shows increased irritation or possible sensitization (redness, itching, burning, blistering, swelling, or oozing).
Terbinafine may be found in breast milk. For this reason, the drug cannot be used in breastfeeding women. Pregnant women should also avoid applying Lamisil.
Lamisil 1% contains 11.3% v/v alcohol. If irritation or sensitivity develops, treatment should be discontinued and appropriate therapy instituted. Lamisil may be irritating to the eyes. In case of accidental contact with the eyes, rinse the eyes thoroughly with running water and consult a physician if any symptoms persist.
Avoid covering the affected areas with dressings unless otherwise directed by the physician.
There has been no experience of overdose with topical formulations of terbinafine. However, the alcohol content (11.3%) of the cream must be considered.
In most clinical cases, side effects are rare and require no medical help. Potential adverse reactions include the following:
In clinical trials, none of the 262 patients treated with Lamisil (Terbinafine) discontinued therapy due to adverse events. For Lamisil (Terbinafine)-treated patients, adverse reactions thought to be possibly, probably, or related to drug therapy included skin disorder (1.9%), application site reactions (burning or irritation) (1.5%), and pruritus (1.1%). The adverse events were seen only in patients with tinea cruris: skin discoloration, hyperpigmentation (3/36), skin exfoliation (1/36), and contact dermatitis (1/36).
Potential interactions between Lamisil (Terbinafine) and other drugs have not been systematically evaluated.
After using Lamisil cream, storing and disposing of it properly is essential.
Lamisil cream should be stored in its original packaging to protect it from light and moisture. It is essential to keep the tube tightly sealed and out of reach of children. The cream should not be used after the expiry date indicated on the packaging, and once opened, an aluminum tube can typically be used for up to four months, while a laminated tube has a shelf life of one month.
When disposing of Lamisil cream, do not throw it away in household waste or down the drain, as this can harm the environment. Instead, consult your pharmacist for proper disposal methods. Unused or expired medications should be returned to a pharmacy for safe disposal to ensure environmental protection.
My tube was delivered in Chicago after sitting in very hot weather. Can I still use the cream?
Check the tube and carton for leaking, damage, separation, unusual color, or texture changes, and keep it at 68°F to 77°F; have any questionable product checked before use.
I used terbinafine in a different form before. What form do you sell for this product?
Our listing is for topical terbinafine cream 1% in tubes. Other terbinafine dosage forms are not listed as options for this product.
My order just arrived. Where on the package can I confirm that I received terbinafine 1% cream?
Check the tube and outer carton for the active ingredient, "terbinafine," the strength, "1%," and the dosage form, "cream." You can also compare the manufacturer name, lot number, expiration date, and any imprint or identifying code present on the package.
My 10-year-old has what looks like ringworm from wrestling. Is this cream appropriate for children?
For terbinafine 1% cream, children under 12 should be assessed by a doctor before use. A clinician can confirm whether it is ringworm and recommend the appropriate treatment for your child.
| Active ingredient | Terbinafine |
|---|---|
| Drug class | Allylamine antifungal |
| Dosage form | Cream |
| Available strengths | 1% |
| Route | Topical |
| Storage | Store at controlled room temperature, 68°F to 77°F, and keep the tube tightly closed. |
| ATC code | D01AE15 |
This product has 6 ratings, but only 3 written reviews so far. Share your experience and help other customers.
The inner packaging stayed secure even after the parcel traveled some distance, and the order arrived undamaged.
I had no problems.
I received the order for terbinafine in a plain outer parcel with no product wording visible.
